CAZyme Information: MGYG000002330_02336

Basic Information

• Species: Eisenbergiella tayi
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; Eisenbergiella tayi
• CAZyme ID: MGYG000002330_02336
• CAZy Family: GH42
• CAZyme Description: Beta-galactosidase III

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
284	MGYG000002330_74|CGC1	32952.49	5.5693

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002330	7416064	Isolate	not provided	not provided

• Gene Location: Start: 56829; End: 57683 Strand: +

Full Sequence      

MALYVGTNYHPHDWTPERWKKDIALMKEAGFQVVRLGHLCWDSYEPQDGVYNFQWFDEVM
DGFYEAGIKVFLDVSVRPAPVWVHKLCPGCDIFTPGGNRQAAVTRYMEDVDDPDYQFYAL
RFAREMVSHYKDHPAMMAFGLCNEQGAGFISYSDAACKRFQVWLKEKYKDIDSLNKAWNT
QRWSRRLNCFEDVVLPCNETSKGAPEAYLEMRRFFGDGVLKFMIKLKDVVEQEAPGMMHS
SNHVSEGDTLGFDYLKGCREFVDYPGVGFYPDLDPGMKIHLYMH

Enzyme Prediction     

No EC number prediction in MGYG000002330_02336.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH42	9	274	1.5e-67	0.7088948787061995

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam02449	Glyco_hydro_42	5.98e-52	9	284	2	280	Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.
COG1874	GanA	1.75e-33	3	222	16	237	Beta-galactosidase GanA [Carbohydrate transport and metabolism].
pfam00150	Cellulase	2.28e-06	10	144	15	130	Cellulase (glycosyl hydrolase family 5).
pfam02836	Glyco_hydro_2_C	1.93e-05	12	148	23	139	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
COG2723	BglB	4.30e-04	17	132	59	158	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AJG98278.1	1.74e-112	5	275	8	279
APO45995.1	5.05e-111	3	278	2	277
AIQ70295.1	1.61e-102	3	275	1	273
SDT03992.1	7.61e-95	1	271	24	296
BAU54053.1	7.94e-92	1	271	15	287

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4UOQ_A	5.56e-45	3	264	23	287	Nucleophilemutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 [Bifidobacterium animalis subsp. lactis Bl-04],4UOQ_B Nucleophile mutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 [Bifidobacterium animalis subsp. lactis Bl-04],4UOQ_C Nucleophile mutant (E324A) of beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 [Bifidobacterium animalis subsp. lactis Bl-04],4UOZ_A beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04],4UOZ_B beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04],4UOZ_C beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 nucleophile mutant E324A in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04]
4UNI_A	5.56e-45	3	264	23	287	beta-(1,6)-galactosidasefrom Bifidobacterium animalis subsp. lactis Bl-04 in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04],4UNI_B beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04],4UNI_C beta-(1,6)-galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 in complex with galactose [Bifidobacterium animalis subsp. lactis Bl-04]
4UCF_A	6.89e-44	3	262	20	284	Crystalstructure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UCF_B Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UCF_C Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose [Bifidobacterium bifidum S17],4UZS_A Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17],4UZS_B Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17],4UZS_C Crystal structure of Bifidobacterium bifidum beta-galactosidase [Bifidobacterium bifidum S17]
6Y2K_A	4.51e-34	3	256	1	254	ChainA, beta-galactosidase [Marinomonas sp. ef1]
5E9A_A	8.45e-33	2	264	38	300	Crystalstructure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_B Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_C Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_D Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_E Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_F Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
D4QFE7	3.77e-43	3	262	20	284	Beta-galactosidase BbgII OS=Bifidobacterium bifidum OX=1681 GN=bbgII PE=3 SV=1
Q93GI5	6.76e-42	4	256	21	274	Beta-galactosidase III OS=Bifidobacterium longum subsp. infantis OX=1682 GN=beta-galIII PE=1 SV=1
P19668	1.83e-39	2	279	6	281	Beta-galactosidase bgaB OS=Geobacillus kaustophilus OX=1462 GN=bgaB PE=1 SV=1
C9S0R2	8.94e-39	2	279	6	281	Beta-galactosidase BgaB OS=Geobacillus sp. (strain Y412MC61) OX=544556 GN=bgaB PE=3 SV=1
A1A399	6.86e-38	2	260	19	280	Beta-galactosidase BgaB OS=Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) OX=367928 GN=bgaB PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000053	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002330_02336.