Species | Mycobacterium avium | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium avium | |||||||||||
CAZyme ID | MGYG000002306_00570 | |||||||||||
CAZy Family | GT53 | |||||||||||
CAZyme Description | putative arabinosyltransferase C | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 1210; End: 4485 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT53 | 25 | 1090 | 0 | 0.998093422306959 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
pfam04602 | Arabinose_trans | 0.0 | 224 | 680 | 1 | 458 | Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. |
pfam14896 | Arabino_trans_C | 0.0 | 717 | 1090 | 1 | 384 | EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate. |
pfam17689 | Arabino_trans_N | 5.69e-53 | 53 | 220 | 2 | 155 | Arabinosyltransferase concanavalin like domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
AJK80906.1 | 0.0 | 1 | 1091 | 1 | 1091 |
AYQ68946.1 | 0.0 | 1 | 1091 | 1 | 1091 |
ASE12825.1 | 0.0 | 1 | 1091 | 1 | 1091 |
AZB12648.1 | 0.0 | 1 | 1091 | 1 | 1091 |
AAS02549.1 | 0.0 | 1 | 1091 | 1 | 1091 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
7BVE_A | 0.0 | 24 | 1090 | 11 | 1072 | Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155] |
7BVH_A | 0.0 | 24 | 1090 | 24 | 1085 | Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155] |
7BVF_B | 6.75e-297 | 23 | 1090 | 21 | 1095 | Cryo-EMstructure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycobacterium tuberculosis H37Rv] |
7BWR_A | 5.73e-295 | 26 | 1090 | 24 | 1079 | Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155] |
6X0O_A | 9.62e-295 | 26 | 1090 | 24 | 1079 | Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P9WNL4 | 0.0 | 8 | 1091 | 9 | 1093 | Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embC PE=3 SV=1 |
Q9CDA7 | 0.0 | 23 | 1091 | 6 | 1070 | Probable arabinosyltransferase C OS=Mycobacterium leprae (strain TN) OX=272631 GN=embC PE=3 SV=1 |
Q7TVN4 | 0.0 | 8 | 1091 | 9 | 1093 | Probable arabinosyltransferase C OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=embC PE=3 SV=1 |
P9WNL5 | 0.0 | 8 | 1091 | 9 | 1093 | Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embC PE=1 SV=1 |
Q50393 | 0.0 | 24 | 1090 | 11 | 1072 | Probable arabinosyltransferase C OS=Mycolicibacterium smegmatis OX=1772 GN=embC PE=3 SV=2 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.999949 | 0.000057 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
start | end |
---|---|
27 | 49 |
231 | 250 |
263 | 285 |
340 | 359 |
372 | 391 |
430 | 452 |
465 | 487 |
529 | 551 |
564 | 581 |
585 | 607 |
620 | 642 |
657 | 679 |
692 | 714 |
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