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CAZyme Information: MGYG000002285_00554

You are here: Home > Sequence: MGYG000002285_00554

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-95 sp900066375
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; CAG-95; CAG-95 sp900066375
CAZyme ID MGYG000002285_00554
CAZy Family GT11
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
321 MGYG000002285_2|CGC7 37920.12 5.3858
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002285 3374269 Isolate China Asia
Gene Location Start: 207813;  End: 208778  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.69

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT11 1 300 6.1e-63 0.9710144927536232

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11301 Fut1_Fut2_like 1.76e-54 1 293 1 258
Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531 Glyco_transf_11 1.80e-17 1 292 1 280
Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.
cd11548 NodZ_like 2.76e-04 1 276 1 280
Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ADL35260.1 3.36e-66 1 307 1 288
AOZ97425.1 1.89e-65 1 307 1 288
SNX52916.1 1.49e-54 1 307 1 287
ADL33161.1 5.27e-50 1 307 5 281
QUO20851.1 5.05e-48 1 289 1 264

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q58YV9 1.22e-23 6 307 5 302
O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000063 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002285_00554.