CAZyme Information: MGYG000002216_00156

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae
• CAZyme ID: MGYG000002216_00156
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
694	MGYG000002216_2|CGC2	80964.34	7.8714

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002216	3003083	MAG	Spain	Europe

• Gene Location: Start: 45722; End: 47806 Strand: -

Full Sequence      

MENESIAYHVDKVATSFGNILIQGWAIDREGKNEIFVEDTKGEKLVIYTERLVRKDVNQV
YGLEKDCQSGFHVVVDMGNITTRKIRLVFANGAEKKSYEVDLHKNRLQNRLRRRLLKDET
IPMDYDEWVREQAPKVRERISQRREHFAWEPLFSVVIPLYNTPIPFLKKIVDSVLGQTYR
KVELCLADGSTSDEAERYLKSRYRRERRMKYMRLRENRGISVNTNRAIAMATGDFIVFAD
HDDTLTIDAFYEMVKALNRDPKIEILYSDEDKVNKTDTNYFGPHLKTVFDMDLLRCNNYI
CHIFAVKREVLDRVGLLRREYDGAQDYDFVLRCCEQSQHIYHIPKVLYHWRVHPQSTAGN
PASKMYAFEAGRRAVEDHYRRMGVEATVESTKMLGRYRTRRAVIGKPLVSVLIPNMDHVQ
ELKTCLNSLFSKTSYDNYEVLIIENNSTEPETFAYYEALQREHERVRIIRWEKAFHYAAM
HNRAVMEAKGEYLLFLNNDVEIRNAGWMEEMLSHCQREEVGAVGAKLYYPDGTIQHAGVV
IGFGGVAGHLFAGTGGDQEGYMAALVSVRQVSAVTAACMMTKKTLYRQVNGMDESFQVAY
NDVDYCLKLRAMEKEIVFTPYARLTHFESKSRGLEDTPQKKKRLMREAKHFAAKWPDILK
NGDPFFNQNLFEIVPEYRNMKYDETFWDRWSEQG

Enzyme Prediction     

No EC number prediction in MGYG000002216_00156.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	154	312	1e-24	0.9764705882352941
GT2	410	541	4.4e-21	0.7588235294117647

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04184	GT2_RfbC_Mx_like	5.75e-93	151	352	1	202	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
cd04186	GT_2_like_c	1.13e-37	411	628	1	166	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
cd06433	GT_2_WfgS_like	1.14e-27	154	357	1	200	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
pfam00535	Glycos_transf_2	1.27e-25	154	311	1	164	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd00761	Glyco_tranf_GTA_type	4.77e-21	155	342	1	156	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBL24562.1	8.98e-217	1	670	117	800
QJU15224.1	9.19e-204	8	670	115	804
ASU27525.1	9.19e-204	8	670	115	804
ANU74720.1	9.19e-204	8	670	115	804
QQQ92268.1	9.19e-204	8	670	115	804

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P55465	2.13e-115	123	670	335	888	Uncharacterized protein y4gI OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) OX=394 GN=NGR_a03550 PE=4 SV=1
Q50864	1.25e-89	124	670	292	831	O-antigen biosynthesis protein RfbC OS=Myxococcus xanthus OX=34 GN=rfbC PE=4 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000071	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002216_00156.