CAZyme Information: MGYG000002140_00193

Basic Information

• Species: CAG-510 sp900551115
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; CAG-510; CAG-510 sp900551115
• CAZyme ID: MGYG000002140_00193
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
628	MGYG000002140_1|CGC7	71458.44	7.2442

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002140	3321781	MAG	United States	North America

• Gene Location: Start: 211716; End: 213602 Strand: +

Full Sequence      

MNLKKIVRRQLEKRLDRKYEKELKRRKLDYTSWLAELESKQKGMPYGKGVAADTDFTLLV
FGKGTVAAGAKERIAAFFAKYPETALLYGDEDVKTEKGVCGNPWLKPDWSPDAYLCRDYL
GSVVAVRKQLFDKLTEQEKQEEGLCHDRLTELAGGFKRGCKSIGHLREIIFHREEVWQLP
GEGRAGRRPESAQEAQDCFCQAAEEKPMVSVIIPSKDNVSVLKQCLTTLCKTAQGIDYEI
IIVDNGSCKHTRDSVSKEVEKINQDLTKQSPLKGAYYLYEPMEFNFSRMCNMGAERAKGN
LLLFLNDDIEAVEQGWFEEMAAKALEPWAGAVGIKLWYPDSDRIQHAGVVNISLGPVHKL
QFLKDNKRYYDGRNIGVWNALAVTGACFMLRKTVFDEAGGFAENIQVAFNDVDLCFTLYE
MGLHNVVVNTRHMLHHESLSRGNDETEEKQKRLLRERNLLYGRHPGLEGKDPYYHPWLNC
NRLDTTIRPAFEEGRTIPDTRDYKLLGSLQGARRDDCLRLAFELTTAYRTQGYAVVLGSD
NACFEKELLFKEKHGSNKLYRFAFTGQYRSDLEENMPDQKNIALSGFKVDFARSLPPGEY
RIGAMATDKISGLTIVNWVNHTLTVQEA

Enzyme Prediction     

No EC number prediction in MGYG000002140_00193.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	210	397	1.4e-16	0.9823529411764705

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04186	GT_2_like_c	2.82e-29	211	437	1	166	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG1216	GT2	6.97e-19	207	461	3	243	Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
pfam00535	Glycos_transf_2	9.81e-17	210	395	1	164	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd04184	GT2_RfbC_Mx_like	5.58e-14	74	173	104	200	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
cd00761	Glyco_tranf_GTA_type	1.83e-11	211	422	1	151	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QNM02107.1	9.69e-162	1	627	1	669
ADL33298.1	1.25e-115	38	626	65	703
AOZ95571.1	1.03e-113	38	627	65	703
QWT52131.1	1.11e-84	80	602	505	1034
AVK48684.1	9.62e-83	52	610	780	1346

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q50864	5.34e-47	55	504	403	866	O-antigen biosynthesis protein RfbC OS=Myxococcus xanthus OX=34 GN=rfbC PE=4 SV=1
P55465	1.04e-42	81	487	476	897	Uncharacterized protein y4gI OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) OX=394 GN=NGR_a03550 PE=4 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000063	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002140_00193.