logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000002121_00415

You are here: Home > Sequence: MGYG000002121_00415

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Acidaminococcus sp000437815
Lineage Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Acidaminococcus; Acidaminococcus sp000437815
CAZyme ID MGYG000002121_00415
CAZy Family GT30
CAZyme Description Tetraacyldisaccharide 4'-kinase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
843 MGYG000002121_4|CGC1 94834.21 8.2392
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002121 1985893 MAG Mongolia Asia
Gene Location Start: 21966;  End: 24497  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002121_00415.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT30 36 216 1.3e-54 0.9717514124293786

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK05749 PRK05749 4.30e-128 1 431 2 422
3-deoxy-D-manno-octulosonic-acid transferase; Reviewed
COG1519 KdtA 2.03e-113 5 430 5 419
3-deoxy-D-manno-octulosonic-acid transferase [Cell wall/membrane/envelope biogenesis].
pfam02606 LpxK 1.78e-86 485 837 2 318
Tetraacyldisaccharide-1-P 4'-kinase. This family consists of tetraacyldisaccharide-1-P 4'-kinase also known as Lipid-A 4'-kinase or Lipid A biosynthesis protein LpxK, EC:2.7.1.130. This enzyme catalyzes the reaction: ATP + 2,3-bis(3-hydroxytetradecanoyl)-D -glucosaminyl-(beta-D-1,6)-2,3-bis(3-hydroxytetradecanoyl)-D-glu cosam inyl beta-phosphate <=> ADP + 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D- glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate. This enzyme is involved in the synthesis of lipid A portion of the bacterial lipopolysaccharide layer (LPS). The family contains a P-loop motif at the N-terminus.
PRK00652 lpxK 4.50e-67 485 838 15 325
tetraacyldisaccharide 4'-kinase; Reviewed
pfam04413 Glycos_transf_N 1.26e-66 36 216 1 176
3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase). Members of this family transfer activated sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. Members of the family transfer UDP, ADP, GDP or CMP linked sugars. The Glycos_transf_N region is flanked at the N-terminus by a signal peptide and at the C-terminus by Glycos_transf_1 (pfam00534). The eukaryotic glycogen synthases may be distant members of this bacterial family.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ADB48040.1 0.0 1 843 1 843
AEQ21866.1 0.0 1 840 1 840
BBG63225.1 0.0 1 839 1 839
QNP77900.1 0.0 1 839 1 839
QTV78313.1 0.0 1 839 1 839

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4EHX_A 1.83e-38 492 799 10 285
Crystalstructure of LpxK from Aquifex aeolicus at 1.9 angstrom resolution [Aquifex aeolicus VF5],4EHY_A Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution [Aquifex aeolicus VF5],4ITL_A Crystal structure of LpxK from Aquifex aeolicus in complex with AMP-PCP at 2.1 angstrom resolution [Aquifex aeolicus VF5],4ITM_A Crystal structure of 'apo' form LpxK from Aquifex aeolicus in complex with ATP at 2.2 angstrom resolution [Aquifex aeolicus VF5],4ITN_A Crystal structure of 'compact P-loop' LpxK from Aquifex aeolicus in complex with chloride at 2.2 angstrom resolution [Aquifex aeolicus VF5],4LKV_A Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5],4LKV_B Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5],4LKV_C Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5],4LKV_D Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK [Aquifex aeolicus VF5]
4EHW_A 1.92e-38 492 799 12 287
Crystalstructure of LpxK from Aquifex aeolicus at 2.3 angstrom resolution [Aquifex aeolicus VF5]
2XCI_A 8.66e-31 53 404 37 350
Membrane-embeddedmonofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCI_B Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCI_C Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCI_D Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, substrate-free form [Aquifex aeolicus],2XCU_A Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus],2XCU_B Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus],2XCU_C Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus],2XCU_D Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP [Aquifex aeolicus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
B8CZC3 4.36e-71 467 821 12 371
Tetraacyldisaccharide 4'-kinase OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=lpxK PE=3 SV=1
Q2LVL1 2.28e-67 488 821 27 357
Tetraacyldisaccharide 4'-kinase OS=Syntrophus aciditrophicus (strain SB) OX=56780 GN=lpxK PE=3 SV=1
A5G6H1 1.51e-66 467 820 7 343
Tetraacyldisaccharide 4'-kinase OS=Geotalea uraniireducens (strain Rf4) OX=351605 GN=lpxK PE=3 SV=1
A1ATF5 2.01e-63 463 838 4 361
Tetraacyldisaccharide 4'-kinase OS=Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1) OX=338966 GN=lpxK PE=3 SV=1
P44806 3.16e-62 34 431 30 424
3-deoxy-D-manno-octulosonic acid transferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=waaA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000046 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
7 26