CAZyme Information: MGYG000002097_00658

Basic Information

• Species: Firm-11 sp900553905
• Lineage: Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; Firm-11; Firm-11 sp900553905
• CAZyme ID: MGYG000002097_00658
• CAZy Family: GT39
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1364	MGYG000002097_22|CGC1	150244.78	5.9854

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002097	2742547	MAG	Mongolia	Asia

• Gene Location: Start: 14302; End: 18396 Strand: -

Full Sequence      

MKRICAFFCLALTLLVCLTAAAEETNLIANGGFETLDASGDPVDWYPTAYRTQEGYSRIA
VTSEKAHSGQYSAVVENASANDARYTCTVSVEPSSLYRLSAYVLVESMEDTGNGANLGIE
GIYSYSDCLFDTDGAWQYLEWYGETGEDQHELTFGVRVGGYGAESTGKAYFDDVCLEKVD
ALPSGVFASLWYDAQSYVSYDVSTTQQTGEKSTVLFVALGLVFGFAYLLARPLLERGGTN
RRAVCAFAGLMAVALAVRIVLAVKVPGYSVDINCFTAWSLRMAERGPAGFYAPDYFCDYP
PGYMLLLWPCGLLLNAVKSAGASLLVVKIMPIMCDMAGALVLFGYARKRLGDAAAALVAG
LYAFSPAVLVNGAAWGQADSVLALLLMLTALAAIRRDWRAALPLFVASVLVKPQALLFAP
VGGVWLLVCLLEKQERPDRMRQWKSVGTGLGLAVVVAAAIIVPFSVQQSPLWLIDLYGET
LSSYAYATLNTANLYYLIGANWTDLAAHVPTALPLVTALAAMSGGLWLLLSGEKLSLRSR
PRSTSLGALCLLLALYQFGLTFFGGSYSAYGYGMTAFAFLLAAVCLACDRKAAALPFYLA
LSLILIYVLGVKVHERYLLPALPLLLLAYVLTRDRRLLALCVGFSITTFINTAIVLDNAI
LFGAEQGHLNNDTLVLNDALCALNLLLCGYAVWLAYTGLRPSEAPIPHEAEPAVPPSYER
MLLSPRDARLRLTLRDYLVMGATCVLYGVLAFTNLGSTVAPQTGWISTSPDEQIVFDLGE
STRFSLLYYAGVSYNDFSVSTSDDGVTWSAETPCRMREGLCYRWLYALQSTQSDGEVTYM
SDSPISVVWFTGRYLRLNACEAGLNLWEIVARDEDGQTLPLTIVSHTGARTGVLESEKPV
ENLIDEQDTCVGEPGWYNGTYFDEIYHARTAYEHLHGQAPYETTHPPLGKLLMSVGIAIF
GMTPFGWRFAGALIGVLMLPALYLLALQLTHRRSIATVSMLAFSLDLMHYTQTRIATIDS
FPVFFILLSYLCMVRYLQTDLFAVDPEKPRLFDRCLRKSLIPLALSGLFIGLAIASKWIG
LYSAVGLALLFFTAVYRQYRVSNVACGLDVEHVKLDDGQKARVRAAQDFTLKRILITCGF
CVIFFVLVPCVIYYLCYIPYLSSTGPVTLKRVIDAQIGMLNYHSTPGLGMDHPFQSPWWQ
WPFILKPMWFAQDQYEPAGYASTIMCMGNPWVFYIGAVAMLGALAACVAKYLNLRAGVSL
RQGDGDLTLPVLAVGFLAQYLPWVLVPRSMYIYHYFASVPFIIMATAWWLDRLPRSRPRL
RTGVMALYLVGALVFFVMFFPYASGWLTNTEWLDAMKWFSKLYY

Enzyme Prediction     

No EC number prediction in MGYG000002097_00658.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT39	918	1160	1.3e-54	0.9147982062780269

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam16192	PMT_4TMC	1.10e-22	1170	1360	1	198	C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
COG1928	PMT1	7.16e-21	916	1165	43	277	Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam02366	PMT	2.01e-16	915	1092	16	197	Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
pfam13231	PMT_2	1.33e-11	945	1097	2	135	Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
COG4346	COG4346	1.46e-08	941	1223	132	339	Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUC68008.1	4.39e-310	2	1364	5	1422
QTE71236.1	5.56e-310	22	1364	11	1407
QTE75201.1	8.74e-310	22	1364	26	1422
QUA53848.1	1.25e-307	2	1354	9	1362
QTE68569.1	3.54e-300	16	1354	24	1392

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
L8F4Z2	2.57e-26	911	1352	56	506	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1
P9WN04	1.15e-23	922	1304	73	457	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05	1.15e-23	922	1304	73	457	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
Q8NRZ6	2.09e-12	945	1359	99	516	Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000253	0.999047	0.000217	0.000155	0.000149	0.000147

TMHMM  Annotations     

start	end
213	230
243	262
305	327
353	375
415	432
445	467
509	531
543	565
570	587
594	611
615	632
637	659
674	696
737	759
965	987
1015	1037
1069	1091
1134	1156
1232	1254
1267	1286
1291	1310
1323	1345