CAZyme Information: MGYG000001809_01489

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella
• CAZyme ID: MGYG000001809_01489
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1232	MGYG000001809_20|CGC1	139044.57	5.3185

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001809	3938122	MAG	Denmark	Europe

• Gene Location: Start: 51004; End: 54702 Strand: -

Full Sequence      

MKFYLKRGQECPVRVSDQETDAVKIAAGNLRTDLTKVFGASSGRQTAEILAGTLGVSPDF
DALVGTERLSHCGLYEEGGKLRREGYVMYVQEGRLVIAGTDRRGTVYGIYELCGMLGVSP
WYFWADVPVKEKETFILPEDFEKADWPSVEYRGIFINDEEELDRWVQKHMGEDTIGVKTY
EKIFELLLRLKANYIWPAMHVNSFNMKKENGALADRMGIVVGTSHCDMLMRSNNREWKPW
IAKKGYTDAVYDYSIPGRNREILQEYWRESVEQNRDFEVCYTLGMRGIHDSGFETEAIMQ
LPEEERKAAKVKLLETVIRDQRKILKETLGHDTMMTFIPYKEVLELYDAGLEVPEDMTLV
WANDNYGYVRRYPSEKEKKRSGGNGLYYHNSYWAPPSMSYVFLCSIPLAHTAYELGKAWR
EGIRKLWVMNVGAMKPLEQEIEFFLRLAWEAGKESAPRFGALSGKREKPLSQDVDAYVAD
WITRNFSSFGNFSSSGKISGSGDVSGGIGTQVSELLNDFSQLTNVRKIENMDDDAFSQTA
YGDEAAVRIHKYEELFERGNAIYAGLPEKERDAFFQLVLMRIHAAYFTNLAYYYGDRSTL
ACRQGKFAAAAEYVQKTRKFDDARRKLLVYYNKRMAQGKWDGILDPEGFPPPRAAMLPGC
TPPLPERLRIRKWPGTATAVGETAEGSAGTGTAGRTGQPEVFVNGRMILSLWNEGRELVF
SGRSVKWLEIGNGAGEETGGFGSTGGFDSLKAFDFEVEAPDWIGLSRKRGSVRTEVRILV
TAEDAARNRTGVIRVKNLTDGGTLEIPVRMVAPDLSGAVSSGAAYGAGRAVPTEDGGLVC
VEADSAEKMSPQFRVIKRAGRCRGNLVECFLSEKEAGEWNEPLNYPVCLVSEGEFLMEIH
RFPSLNSTGRIRIGVSVDGGGIQIVETPSTDEWRGNWKKNVLNNVDRLYLRLPYLEAGVH
EICLHGIDRYFAFSRFVIYTQERRENNLAGVTGCQALPKEWNVDQWLEGFYGRIELKPRA
ELWEPVRVSSDNLEAGDLVRLPERYADPVSPEYYFEAGKTPFEEKKGQIRIDAAAALSNS
ESAWLSDDRWQYCAGETFGRSGLAMYIRNAGTSWEDEKEAPCLNYRIRMEGGSYYIWLLC
RFGLKEESRALAGMDGKALAPLPGHRDGFLWRYEAEQVYRWVPLAKTEAAPGEHTLQIFC
MTSGMRFERICLVKGEDLPPADLEWKLCDAPE

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	6	646	6.9e-175	0.812051649928264

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	6.64e-136	145	529	1	333	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.44e-14	834	980	4	160	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	4.05e-04	37	112	26	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).
pfam02838	Glyco_hydro_20b	0.007	23	109	11	101	Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QOV19968.1	0.0	1	1225	2	1120
AIQ48273.1	0.0	13	1226	12	1201
AIQ53763.1	0.0	13	1226	12	1201
AJE49570.1	0.0	5	1225	14	1207
QOH62055.1	0.0	5	1225	14	1207

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5BY3_A	4.58e-91	3	645	20	616	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4C90_A	1.35e-79	8	644	50	640	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
4ZMH_A	2.01e-79	15	641	27	607	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
7PUG_A	7.81e-78	5	644	20	625	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	4.11e-76	5	644	19	624	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000057	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001809_01489.