Species | Paraprevotella sp900760455 | |||||||||||
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Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella; Paraprevotella sp900760455 | |||||||||||
CAZyme ID | MGYG000001659_01545 | |||||||||||
CAZy Family | GH33 | |||||||||||
CAZyme Description | Sialidase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 18248; End: 19486 Strand: - |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GH33 | 40 | 393 | 2.3e-49 | 0.9327485380116959 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd15482 | Sialidase_non-viral | 1.15e-64 | 41 | 400 | 10 | 339 | Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases. |
pfam13088 | BNR_2 | 1.03e-08 | 68 | 287 | 10 | 205 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
COG4409 | NanH | 3.44e-07 | 14 | 158 | 255 | 411 | Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]. |
pfam15902 | Sortilin-Vps10 | 0.001 | 82 | 229 | 5 | 112 | Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
ALO48969.1 | 8.77e-127 | 6 | 409 | 3 | 399 |
QFQ12979.1 | 9.75e-124 | 44 | 409 | 33 | 397 |
QYR10380.1 | 2.69e-121 | 19 | 410 | 15 | 396 |
EFC70822.1 | 1.01e-118 | 26 | 409 | 14 | 402 |
QUB70796.1 | 2.69e-95 | 6 | 412 | 11 | 431 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
1EUR_A | 6.22e-18 | 45 | 386 | 25 | 344 | Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens] |
1EUT_A | 1.63e-17 | 45 | 386 | 25 | 344 | Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens] |
1WCQ_A | 5.15e-17 | 45 | 386 | 21 | 340 | Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens] |
1W8N_A | 5.15e-17 | 45 | 386 | 21 | 340 | Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens] |
2BZD_A | 9.17e-17 | 45 | 386 | 21 | 340 | Galactoserecognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_B Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_C Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
Q02834 | 9.42e-17 | 45 | 386 | 67 | 386 | Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1 |
P15698 | 3.87e-15 | 41 | 272 | 50 | 277 | Sialidase OS=Paeniclostridium sordellii OX=1505 PE=1 SV=1 |
P10481 | 2.66e-14 | 41 | 275 | 32 | 262 | Sialidase OS=Clostridium perfringens OX=1502 GN=nanH PE=1 SV=1 |
P31206 | 1.76e-09 | 41 | 272 | 199 | 429 | Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2 |
O35657 | 4.22e-09 | 45 | 258 | 71 | 274 | Sialidase-1 OS=Mus musculus OX=10090 GN=Neu1 PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.000249 | 0.999072 | 0.000194 | 0.000180 | 0.000144 | 0.000135 |
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