CAZyme Information: MGYG000001367_00086

Basic Information

• Species: Clostridium_Q symbiosum
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Clostridium_Q; Clostridium_Q symbiosum
• CAZyme ID: MGYG000001367_00086
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1130	MGYG000001367_1|CGC1	126517.22	4.325

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001367	4857868	Isolate	not provided	not provided

• Gene Location: Start: 102499; End: 105891 Strand: +

Full Sequence      

MKKRKATLCLALAAVFGISSVAGCSKTPNNSGQDEKAAESQAGSAVGGADGSGDGSGSSG
ESTAIKEAGPDPNASVFAGEEWFDQRGTFEVNREKAHTSFISFASEEDARVREKEKSPFY
QSLNGIWKFQLVDSPHQRNTEFYRTDYDVSGWDNIDVPSNWQTEGFDYPKYTDTRLPWEG
VEIPELGVSPTLYNPVGSYRRDFKTPENWDGKEVFVSFQGVESAFYVWVNGEYAGYSEDS
YTAAEFNISPYLNAAGENNTIAVQVYRWSDGSYLEDQDFIRLSGIFRDVFLYSKDRGASI
FDFNYTTDLDDSYVDAVMNIEAVLRRFDESAGGGHTLETALLDKDGKEVFRKTLPVTFDG
EEAVISEQVSVSNPAKWSAEEPNLYQMVLTLKDSGGSILESAGCNVGFREVSIINNGTNQ
AQVVINGQPIMFKGVNRHETEPQGGRHITEESMIQDILLMKQHNINSVRNSHYPNEPRWY
ELCDEYGLYMIDEANIESHGLNDYIPQSDPEWMKACRDRMTSTIERSKTHPSILLWSLGN
ESYNGDTWADLGRLCKELDPSRLVHYEGDRDIPEVDVWSRMYRRVNKPDVMDKTANPLVW
WGNYGTKPALQCEYAHAMGNGIGNLKEYWDIYEKYPILQGGFIWDWVDQTVEMPVPAEKR
LKNDAGDLAITLKGSLEDGGNEGKAMKGYAVCYNDKALAFSGKMPFTLEAYVYPEDTVAS
TPIITKGNDEWKCTESYGLQRKVFFNQETGDPVEDYLEFYIYNTEWNEDDGVYTKVSASI
PTPDNWTGQWHRIAGTFDGENLKLYLDGKEVAAAKDSHGIARGGNAVGIGADVTYDAQNP
NVPPVFKGLIDNVRIYNKALTPDEIKKTSRKPDENALVWLDFEGAEDVTYPQPTYYSFGG
DWQDIPAGNPNNKNFCANGLVSADRTVQPELVEVKKLYQNIGLENGDVMNGKILTKNKYL
FTNLNRFNGSWELIEDGKVIQSGIFAPEELNIAPLEEGILTAAFTTPEFKPGAEYFLNVS
FILKEDTSWAKAGHEVAKEQFYLPFNVPKADASEAEMDPLTVEEADAAVNVEGKDFDLVF
NKKTGTIDSFRFNGIDLIKNGPVPNFWRAPTDSDLGFYSQLEMADWRYAG

Enzyme Prediction     

EC	3.2.1.23

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	108	657	5.9e-157	0.5957446808510638

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK09525	lacZ	0.0	91	649	25	574	beta-galactosidase.
PRK10340	ebgA	0.0	92	652	13	551	cryptic beta-D-galactosidase subunit alpha; Reviewed
COG3250	LacZ	1.40e-138	121	649	13	502	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam02836	Glyco_hydro_2_C	2.88e-93	422	668	7	258	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10340	ebgA	1.20e-43	879	1121	545	778	cryptic beta-D-galactosidase subunit alpha; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEE90937.1	0.0	80	1130	32	1040
CDI40488.1	0.0	80	1130	32	1040
QTM99132.1	0.0	81	1130	32	1030
AIQ34883.1	5.88e-307	73	1130	26	1062
QAS61846.1	9.54e-293	79	1130	40	1075

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6S6Z_A	9.34e-162	94	1129	15	773	Structureof beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_B Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_C Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_D Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_E Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_F Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_G Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8],6S6Z_H Structure of beta-Galactosidase from Thermotoga maritima [Thermotoga maritima MSB8]
6SD0_A	9.57e-162	94	1129	16	774	Structureof beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_B Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_C Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8],6SD0_D Structure of beta-galactosidase from Thermotoga maritima. [Thermotoga maritima MSB8]
1F4A_A	4.26e-129	71	651	3	573	E.COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4A_B E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4A_C E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4A_D E. COLI (LACZ) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-ORTHORHOMBIC) [Escherichia coli],1F4H_A E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli],1F4H_B E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli],1F4H_C E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli],1F4H_D E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC) [Escherichia coli]
5A1A_A	4.36e-129	71	651	4	574	2.2A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12],5A1A_B 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12],5A1A_C 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12],5A1A_D 2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor [Escherichia coli K-12]
1JZ2_A	4.46e-129	71	651	5	575	E.COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE (ORTHORHOMBIC) [Escherichia coli],1JZ2_B E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE (ORTHORHOMBIC) [Escherichia coli],1JZ2_C E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE (ORTHORHOMBIC) [Escherichia coli],1JZ2_D E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE (ORTHORHOMBIC) [Escherichia coli],4V40_A BETA-GALACTOSIDASE [Escherichia coli],4V40_B BETA-GALACTOSIDASE [Escherichia coli],4V40_C BETA-GALACTOSIDASE [Escherichia coli],4V40_D BETA-GALACTOSIDASE [Escherichia coli],4V40_E BETA-GALACTOSIDASE [Escherichia coli],4V40_F BETA-GALACTOSIDASE [Escherichia coli],4V40_G BETA-GALACTOSIDASE [Escherichia coli],4V40_H BETA-GALACTOSIDASE [Escherichia coli],4V40_I BETA-GALACTOSIDASE [Escherichia coli],4V40_J BETA-GALACTOSIDASE [Escherichia coli],4V40_K BETA-GALACTOSIDASE [Escherichia coli],4V40_L BETA-GALACTOSIDASE [Escherichia coli],4V40_M BETA-GALACTOSIDASE [Escherichia coli],4V40_N BETA-GALACTOSIDASE [Escherichia coli],4V40_O BETA-GALACTOSIDASE [Escherichia coli],4V40_P BETA-GALACTOSIDASE [Escherichia coli]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O52847	1.04e-195	81	1129	19	822	Beta-galactosidase OS=Priestia megaterium (strain DSM 319 / IMG 1521) OX=592022 GN=bgaM PE=3 SV=1
Q56307	5.24e-161	94	1129	16	774	Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2
Q9K9C6	1.53e-150	82	1116	9	784	Beta-galactosidase OS=Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) OX=272558 GN=lacZ PE=3 SV=1
P24131	1.10e-134	81	668	9	580	Beta-galactosidase OS=Clostridium acetobutylicum OX=1488 GN=cbgA PE=2 SV=2
A1SWB8	5.75e-134	74	1116	5	806	Beta-galactosidase OS=Psychromonas ingrahamii (strain 37) OX=357804 GN=lacZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000000	0.000001	1.000061	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001367_00086.