logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001313_01852

You are here: Home > Sequence: MGYG000001313_01852

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides eggerthii
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides eggerthii
CAZyme ID MGYG000001313_01852
CAZy Family GH137
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1427 MGYG000001313_19|CGC1 163849.98 7.4614
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001313 4157999 Isolate not provided not provided
Gene Location Start: 46972;  End: 51255  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.31 3.2.1.185

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH137 23 371 7.9e-155 0.9941176470588236
GH2 377 815 4.7e-72 0.4853723404255319
CBM57 1089 1251 1.9e-43 0.9863945578231292

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam11721 Malectin 1.06e-36 1087 1245 1 147
Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognizes and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan.
COG3250 LacZ 3.17e-30 380 787 10 407
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 2.67e-18 435 807 110 469
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam00703 Glyco_hydro_2 7.58e-15 544 652 1 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10150 PRK10150 3.38e-13 434 818 65 449
beta-D-glucuronidase; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QRQ48836.1 0.0 1 1427 1 1427
QUT45339.1 0.0 1 1427 1 1427
AND20298.1 0.0 1 1427 1 1423
QJR76292.1 0.0 1 1427 1 1423
ALK84974.1 0.0 1 1427 1 1434

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MUI_A 1.91e-202 1 378 7 381
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482]
5MT2_A 4.93e-195 11 378 14 381
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482],5MUJ_A BT0996 RGII Chain B Complex [Bacteroides thetaiotaomicron VPI-5482]
6D50_A 2.55e-41 371 1223 24 853
Bacteroidesuniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii],6D50_B Bacteroides uniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii]
6D8G_A 3.38e-41 371 1223 24 853
D341AD367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii],6D8G_B D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii]
5UJ6_A 7.53e-41 378 1223 23 845
CrystalStructure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],5UJ6_B Crystal Structure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],6NZG_A Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis],6NZG_B Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
T2KM09 1.01e-32 377 1091 43 756
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KN75 1.42e-26 378 1038 24 672
Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1
O52847 2.15e-20 375 807 51 501
Beta-galactosidase OS=Priestia megaterium (strain DSM 319 / IMG 1521) OX=592022 GN=bgaM PE=3 SV=1
Q56307 2.92e-20 435 819 111 473
Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2
A1SWB8 2.53e-17 450 820 135 489
Beta-galactosidase OS=Psychromonas ingrahamii (strain 37) OX=357804 GN=lacZ PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000273 0.999102 0.000175 0.000149 0.000134 0.000127

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001313_01852.