CAZyme Information: MGYG000001223_00866

Basic Information

• Species: Collinsella sp900758845
• Lineage: Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Coriobacteriaceae; Collinsella; Collinsella sp900758845
• CAZyme ID: MGYG000001223_00866
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
749	MGYG000001223_12|CGC2	85487.87	6.7589

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001223	2100982	MAG	Austria	Europe

• Gene Location: Start: 21783; End: 24032 Strand: -

Full Sequence      

MSVHELKKAKKSVVEKQGARKRDVTTFIVTAVLMVIYLLWRLLFTLPFDQGIPQMVFAVL
LLIAETVTAFTTFELYYRKVKADSGHLVMPKILPEDYPDVDVVIATHNEPTDVLFKTANA
CTYMDYPDRSRVHVYFADDGCRKEVASLAAELGIGYIPCEDNKYAKSGNLNNALRHTTSP
LIATFDADMIPRSSFLVDTVPYFLLPRYIQDGATGAWRYRSEDELNEDLKVGLIQTPQSF
YNLDLFQFNLYAEDKIPNEQDFFSREVNRMRNSSNACAYTGSNAVISRAGMEEIGGFPYH
TITEDFETSCRLQMAGYITYATDKVEAHGLSTTDVRSMVHQRIRWARGVIQSIQNTGVIF
SRKISFSARITYLCSFLYWWSFFNRIIFILAPIMFALFDFQVVNCTLWQLLIFWLPSYFF
YSRSMKLLSSNVRSQKWSQIIDTTLAPSLIIPVFLETLDIRETKFKVTRKDKTTNRSGSL
WNMLPHLLLVVLSVAAIIRFTWGKYGMALVYSSVIIYWLCYNLIALLYAIAFSGGRSMPR
KSTRISVDEPAVLTALPVEDEWSKLAEDTGEAVVEGGVSLDCSSDAMDGEGPVGVFAGRA
INMSDGGVLVRIDDPFPEELRSFAVRLGDGRYCTCVSGRLVRLFQSKCGDDESWYAALRI
EHRSLEERRIYDQLLYDRETGIAEELDSWNTTYDDIVRIVRMRIRALLSRYRVWRSRRRS
RRDSDRCGDSRDAERTSHDSAHVEGDAAC

Enzyme Prediction     

No EC number prediction in MGYG000001223_00866.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	99	348	2.3e-21	0.991304347826087

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06421	CESA_CelA_like	5.09e-78	98	351	1	232	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.
PRK11498	bcsA	2.00e-71	31	553	185	696	cellulose synthase catalytic subunit; Provisional
COG1215	BcsA	4.02e-44	29	526	1	427	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd06435	CESA_NdvC_like	1.99e-29	107	351	7	230	NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response.
cd06423	CESA_like	2.81e-18	102	305	1	180	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SMF90406.1	7.88e-247	20	704	4	651
QLG37677.1	4.98e-240	21	704	5	651
QOS81892.1	9.99e-240	21	704	5	651
QKS57765.1	1.30e-237	21	704	5	651
QNK55597.1	3.19e-237	21	704	5	658

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7LBY_A	1.20e-57	37	591	213	742	ChainA, Cellulose synthase catalytic subunit [UDP-forming] [Escherichia coli K-12]
5EJ1_A	3.40e-52	31	551	62	579	ChainA, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]
4HG6_A	7.23e-52	31	551	74	591	ChainA, Cellulose Synthase Subunit A [Cereibacter sphaeroides]
4P00_A	7.30e-52	31	551	75	592	ChainA, Cellulose Synthase A subunit [Cereibacter sphaeroides 2.4.1],4P02_A Chain A, Cellulose Synthase subunit A [Cereibacter sphaeroides 2.4.1],5EIY_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1],5EJZ_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q8X5L7	2.32e-57	37	591	213	742	Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli O157:H7 OX=83334 GN=bcsA PE=3 SV=2
P37653	5.82e-57	37	591	213	742	Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli (strain K12) OX=83333 GN=bcsA PE=1 SV=3
Q93IN2	6.86e-56	37	591	213	742	Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=bcsA PE=3 SV=1
P58931	1.06e-55	37	550	99	592	Cellulose synthase catalytic subunit [UDP-forming] OS=Pseudomonas fluorescens (strain SBW25) OX=216595 GN=bcsA PE=3 SV=2
Q8Z291	1.26e-55	37	591	213	742	Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhi OX=90370 GN=bcsA PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000040	0.000005	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
26	45
55	77
376	398
402	421
478	500
510	532