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CAZyme Information: MGYG000000909_01385

You are here: Home > Sequence: MGYG000000909_01385

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA9502 sp900538475
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UBA9502; UBA9502 sp900538475
CAZyme ID MGYG000000909_01385
CAZy Family PL8
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1632 MGYG000000909_10|CGC2 179364.34 4.2597
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000909 3035568 MAG China Asia
Gene Location Start: 56019;  End: 60917  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000909_01385.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL8 597 888 2.2e-79 0.9884169884169884

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 4.47e-171 200 961 1 693
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam02278 Lyase_8 5.70e-94 597 887 1 251
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam08124 Lyase_8_N 1.48e-54 224 555 19 322
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
NF033840 PspC_relate_1 1.67e-20 1498 1631 505 648
PspC-related protein choline-binding protein 1. Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.
COG5263 COG5263 3.38e-20 1506 1630 175 313
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ASM70662.1 0.0 4 1017 22 1010
SET74231.1 0.0 49 1631 379 1914
ASM68536.1 0.0 79 1017 11 927
AEB76773.1 7.64e-142 164 988 44 837
QPW61069.1 1.03e-141 156 988 96 897

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6F2P_A 1.72e-100 198 991 3 726
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]
1X1H_A 2.80e-96 198 1018 1 752
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]
1J0M_A 3.81e-96 198 1018 1 752
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
2E22_A 5.19e-96 198 1018 1 752
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
2E24_A 5.19e-96 198 1018 1 752
ChainA, Xanthan lyase [Bacillus sp. GL1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 1.24e-93 198 1018 26 777
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q59801 4.70e-59 321 885 177 691
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
Q54873 5.62e-58 143 923 238 954
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
Q53591 3.53e-53 270 914 311 926
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
P0CZ01 1.26e-42 278 1005 107 789
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000267 0.999029 0.000171 0.000187 0.000168 0.000144

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000909_01385.