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CAZyme Information: MGYG000000658_00375

You are here: Home > Sequence: MGYG000000658_00375

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotellamassilia;
CAZyme ID MGYG000000658_00375
CAZy Family GH33
CAZyme Description Sialidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
400 MGYG000000658_2|CGC2 43388.72 7.5735
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000658 1755704 MAG Germany Europe
Gene Location Start: 81930;  End: 83132  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000658_00375.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 20 378 2.5e-45 0.9473684210526315

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 1.33e-59 22 388 1 339
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
COG4409 NanH 1.62e-07 16 128 255 387
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QFQ12979.1 3.30e-197 1 397 1 397
EFC70822.1 2.14e-150 7 397 6 402
ALO48969.1 2.93e-111 24 397 29 399
QYR10380.1 1.33e-110 14 398 16 396
QFQ13500.1 2.50e-81 29 398 632 1008

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1EUR_A 3.40e-17 32 378 21 348
Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens]
1EUT_A 8.20e-17 32 378 21 348
Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens]
1W8N_A 1.94e-16 32 378 17 344
Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens]
1WCQ_A 2.59e-16 32 378 17 344
Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens]
2BZD_A 4.62e-16 32 378 17 344
Galactoserecognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_B Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_C Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q02834 4.72e-16 32 378 63 390
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
A6BMK7 4.02e-09 16 249 56 282
Sialidase-1 OS=Bos taurus OX=9913 GN=NEU1 PE=2 SV=2
Q5RAF4 2.23e-08 16 249 56 282
Sialidase-1 OS=Pongo abelii OX=9601 GN=NEU1 PE=2 SV=1
Q99519 2.23e-08 16 249 56 282
Sialidase-1 OS=Homo sapiens OX=9606 GN=NEU1 PE=1 SV=1
A5PF10 5.25e-08 16 249 57 283
Sialidase-1 OS=Sus scrofa OX=9823 GN=NEU1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000277 0.999035 0.000189 0.000176 0.000163 0.000145

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000658_00375.