CAZyme Information: MGYG000000583_01293

Basic Information

• Species: Acetatifactor sp900766575
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Acetatifactor; Acetatifactor sp900766575
• CAZyme ID: MGYG000000583_01293
• CAZy Family: GH2
• CAZyme Description: Beta-glucuronidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
605		69533.18	4.979

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000583	2865631	MAG	Madagascar	Africa

• Gene Location: Start: 38166; End: 39983 Strand: +

Full Sequence      

MLYPKMNRSRTIVDLGGIWKFKLGDETEPGESWAELQDADIIYVPASFNDQKEDPAYRNH
YGWVYYERTVELPVCLCTEQNRQVLRFDAVTHAAKIYINSKLASTHTGGFLPFEVDITAL
LPEDGRLTIGVAADNRVSHSTLPVGNEDSIAFFGSDNPGIPSVEAAKKWRKKQNMPNFDF
FNFAGINRPVRIYSTPASYIEDITLVPSLEGDTGVLNYEITTAGVCSDAPVSLKILDADG
KCQAESTGSAGQLRIPRVHLWWPYPGTPYLYKAEVHYGEDTYTEEFGFRTVEVRGTQFLI
NGEPFYFKGFSKHEDSPFHGRGLDLCLDVKDINLLHWMHANSFRTSHYPYAEEIYQLCDR
EGIVIIDETPAVGIGAGSTADPYKTFPIREHHEQVLRDMITRDKNHPCVVMWSMGNEPDT
EHFPESAYDYWHSLYELTHKLDPQNRPVTFVCCQNNYEKDIVTRTMDVVCLNRYYGWYNL
SGDLEAASYAWNLELDFWEKLGNPVMMTEYGADTLPGLHNCVPEMFSEEFQVEFYKMYSK
AFDGRTFFIGEQVWNFADFATIQGCMRADGNRKGIFTRDRRPKMIAHYFRERWEKIPDFG
YKKNE

Enzyme Prediction     

EC	3.2.1.31

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	7	585	8.6e-107	0.6037234042553191

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK10150	PRK10150	0.0	1	603	1	602	beta-D-glucuronidase; Provisional
COG3250	LacZ	2.09e-110	7	595	7	597	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam02836	Glyco_hydro_2_C	2.61e-80	291	596	1	300	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK09525	lacZ	7.00e-34	15	448	55	485	beta-galactosidase.
PRK10340	ebgA	7.34e-32	9	469	38	486	cryptic beta-D-galactosidase subunit alpha; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CUO31707.1	0.0	1	602	1	600
AEN95939.1	0.0	1	602	6	605
CBL12719.1	0.0	1	603	1	600
CBL08206.1	0.0	1	602	1	599
VCV23245.1	0.0	1	602	1	599

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6U7I_A	1.03e-278	1	602	1	597	Faecalibacteriumprausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_B Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_C Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_D Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii]
6LD0_A	8.34e-230	1	602	3	669	ChainA, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD0_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LD6_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDB_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDC_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_A Chain A, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_B Chain B, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_C Chain C, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1],6LDD_D Chain D, LacZ1 Beta-galactosidase [Bifidobacterium dentium Bd1]
5Z1B_A	1.43e-228	1	602	25	691	Structureof Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679],5Z1B_B Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679],5Z1B_C Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679],5Z1B_D Structure of Bifidobacterium dentium beta-glucuronidase complexed with coumarin-3-O-glucuronide [Bifidobacterium dentium ATCC 27679]
6BO6_A	2.62e-206	1	602	1	609	Eubacteriumeligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate [[Eubacterium] eligens ATCC 27750]
6D4O_A	2.90e-206	1	602	4	612	Eubacteriumeligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate [Lachnospira eligens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q4FAT7	5.18e-151	1	596	28	629	Beta-glucuronidase OS=Sus scrofa OX=9823 GN=GUSB PE=3 SV=1
P05804	2.04e-149	1	602	1	596	Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2
O18835	1.27e-148	1	596	27	628	Beta-glucuronidase OS=Canis lupus familiaris OX=9615 GN=GUSB PE=1 SV=1
O97524	1.42e-147	1	596	27	628	Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1
P08236	1.13e-146	1	596	27	629	Beta-glucuronidase OS=Homo sapiens OX=9606 GN=GUSB PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000046	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000583_01293.