CAZyme Information: MGYG000000515_01282

Basic Information

• Species: UBA2882 sp900549665
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UBA2882; UBA2882 sp900549665
• CAZyme ID: MGYG000000515_01282
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
780	MGYG000000515_5|CGC1	90701.4	7.5706

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000515	2818145	MAG	Fiji	Oceania

• Gene Location: Start: 3133; End: 5475 Strand: -

Full Sequence      

MKQTVKTDLKNLIWDWSNKWWFALNIFCTIIYLMWRIFFTIPFGYGFVSVFVGIALLIVE
TLGMVEALVHYANMYNTRDYPKPDVPLELFPDVDVFISTYNEDIVLLAKTICACKRMEYP
DKNKVHIYLCDDGHRETMKMLASQLGVHYLDRETHEGQKAGNLNNALAHSHSPYILTLDA
DMLPQSCFLMETIPYCVDAELRNKDKKPEDQVKLGFIQTPQAFYDLDLFQFNLHSEQKIP
NEQDYFYRDIEVARTRTNSCIYGGSNTIISREALNDIGGFYMDAITEDFATGLLIQKKGY
VSLGLGKVLASGMSANELQNLIQQRVRWARGVISTGRKMHIFTSKDLSFGQKMNYWASIW
YWYAPVKRFFYILSPILYAVFGYMIFRCSLPEVLIFWLPMYVTSNISLKRLSNNIRNTKW
TSIYEYALFPYMLLPVLLETFGISLKKFKVTNKGSVEEDASGKLVYQMPFVLLIVLSVIG
IINCIKVMFDSGSMGPIVVLFWLIVNLYNMVMCLFFISGRKTYRKSERVEVQLPAVLHVN
GKDYPCMTRDISETGAAIYMDEPHLLNVYEKSGVSLEIQDRNYHTEMMCEIKFTKEEKSR
EKPWLYTMEFIGFKSERGYDNLLGICYDRIPTKPQGLQKKTGIYDDLSTNIGRRSVPVFR
LKRYFPRIEIHNTLSYASASGRGMAKIVDFNYQFFLIDGEPLEHEIMFQLAGHNLKTKLS
RKIRNMCLYEVQNFEEIYNDQNVCDEIMEAILKLRTRQIEEPVVEKKKNNLHSFNEMDLV

Enzyme Prediction     

No EC number prediction in MGYG000000515_01282.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	94	277	2.6e-18	0.9882352941176471

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06421	CESA_CelA_like	3.36e-82	91	335	1	233	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.
PRK11498	bcsA	3.04e-77	32	571	200	731	cellulose synthase catalytic subunit; Provisional
COG1215	BcsA	2.41e-41	33	482	1	402	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd06437	CESA_CaSu_A2	8.71e-22	91	331	1	231	Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal.
cd06423	CESA_like	5.02e-19	95	288	1	180	CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AFL98797.1	1.35e-255	21	739	21	731
BBF45458.1	1.08e-238	21	743	5	711
AAK79528.1	6.88e-226	17	737	9	726
AWV81228.1	6.88e-226	17	737	9	726
ADZ20613.1	6.88e-226	17	737	9	726

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7LBY_A	4.82e-69	23	558	206	731	ChainA, Cellulose synthase catalytic subunit [UDP-forming] [Escherichia coli K-12]
5EJ1_A	1.22e-51	32	563	68	610	ChainA, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]
4HG6_A	2.56e-51	32	563	80	622	ChainA, Cellulose Synthase Subunit A [Cereibacter sphaeroides]
4P00_A	2.58e-51	32	563	81	623	ChainA, Cellulose Synthase A subunit [Cereibacter sphaeroides 2.4.1],4P02_A Chain A, Cellulose Synthase subunit A [Cereibacter sphaeroides 2.4.1],5EIY_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1],5EJZ_A Chain A, Putative cellulose synthase [Cereibacter sphaeroides 2.4.1]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q8X5L7	1.18e-68	23	558	206	731	Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli O157:H7 OX=83334 GN=bcsA PE=3 SV=2
P37653	2.21e-68	23	558	206	731	Cellulose synthase catalytic subunit [UDP-forming] OS=Escherichia coli (strain K12) OX=83333 GN=bcsA PE=1 SV=3
Q93IN2	5.85e-68	23	558	206	731	Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=bcsA PE=3 SV=1
Q8Z291	8.02e-68	23	558	206	731	Cellulose synthase catalytic subunit [UDP-forming] OS=Salmonella typhi OX=90370 GN=bcsA PE=3 SV=1
P58931	1.32e-66	23	571	90	630	Cellulose synthase catalytic subunit [UDP-forming] OS=Pseudomonas fluorescens (strain SBW25) OX=216595 GN=bcsA PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000015	0.000002	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
21	43
47	69
369	391
423	445
465	482
497	519