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CAZyme Information: MGYG000000317_01753
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Haemophilus_D parainfluenzae | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Pasteurellaceae; Haemophilus_D; Haemophilus_D parainfluenzae | |||||||||||
| CAZyme ID | MGYG000000317_01753 | |||||||||||
| CAZy Family | CE11 | |||||||||||
| CAZyme Description | UDP-3-O-acyl-N-acetylglucosamine deacetylase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 26961; End: 27878 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| CE11 | 4 | 276 | 8.6e-122 | 0.992619926199262 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG0774 | LpxC | 0.0 | 1 | 302 | 1 | 300 | UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell wall/membrane/envelope biogenesis]. |
| PRK13186 | lpxC | 0.0 | 1 | 299 | 1 | 295 | UDP-3-O-acyl-N-acetylglucosamine deacetylase. |
| TIGR00325 | lpxC | 0.0 | 2 | 301 | 1 | 297 | UDP-3-0-acyl N-acetylglucosamine deacetylase. UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| pfam03331 | LpxC | 1.84e-180 | 4 | 277 | 1 | 271 | UDP-3-O-acyl N-acetylglycosamine deacetylase. The enzymes in this family catalyze the second step in the biosynthetic pathway for lipid A. |
| PRK13188 | PRK13188 | 1.82e-88 | 1 | 275 | 2 | 298 | bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QOR05476.1 | 2.67e-221 | 1 | 305 | 1 | 305 |
| CBW15361.1 | 3.79e-221 | 1 | 305 | 1 | 305 |
| QOR07314.1 | 7.66e-221 | 1 | 305 | 1 | 305 |
| QOR11008.1 | 1.54e-220 | 1 | 305 | 1 | 305 |
| QOR16448.1 | 1.54e-220 | 1 | 305 | 1 | 305 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4MDT_A | 1.38e-174 | 1 | 304 | 1 | 304 | Structureof LpxC bound to the reaction product UDP-(3-O-(R-3-hydroxymyristoyl))-glucosamine [Escherichia coli],4MDT_B Structure of LpxC bound to the reaction product UDP-(3-O-(R-3-hydroxymyristoyl))-glucosamine [Escherichia coli],4MDT_C Structure of LpxC bound to the reaction product UDP-(3-O-(R-3-hydroxymyristoyl))-glucosamine [Escherichia coli],4MDT_D Structure of LpxC bound to the reaction product UDP-(3-O-(R-3-hydroxymyristoyl))-glucosamine [Escherichia coli] |
| 4MQY_A | 1.96e-174 | 1 | 304 | 1 | 304 | CrystalStructure of the Escherichia coli LpxC/LPC-138 complex [Escherichia coli] |
| 3NZK_A | 2.44e-174 | 1 | 304 | 6 | 309 | Structureof LpxC from Yersinia enterocolitica Complexed with CHIR090 Inhibitor [Yersinia enterocolitica],3NZK_B Structure of LpxC from Yersinia enterocolitica Complexed with CHIR090 Inhibitor [Yersinia enterocolitica] |
| 3P3G_A | 6.65e-174 | 1 | 300 | 1 | 300 | CrystalStructure of the Escherichia coli LpxC/LPC-009 complex [Escherichia coli IHE3034],3PS1_A Crystal structure of the Escherichia Coli LPXC/LPC-011 complex [Escherichia coli IHE3034],3PS2_A Crystal structure of the Escherichia Coli LPXC/LPC-012 complex [Escherichia coli IHE3034],3PS3_A Crystal structure of the Escherichia Coli LPXC/LPC-053 complex [Escherichia coli IHE3034],4IS9_A Crystal Structure of the Escherichia coli LpxC/L-161,240 complex [Escherichia coli IHE3034],4IS9_B Crystal Structure of the Escherichia coli LpxC/L-161,240 complex [Escherichia coli IHE3034],4ISA_A Crystal Structure of the Escherichia coli LpxC/BB-78485 complex [Escherichia coli IHE3034] |
| 5U3B_A | 3.64e-131 | 1 | 300 | 1 | 299 | Pseudomonasaeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],5U3B_B Pseudomonas aeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],6MAE_A CHAIN A. UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase PA-LPXC Complexed with (R)-3-((S)-3-(4-(cyclopropylethynyl)phenyl)-2-oxooxazolidin-5-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)propenamide [Pseudomonas aeruginosa PAO1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q0I1C7 | 7.68e-206 | 1 | 305 | 1 | 305 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Haemophilus somnus (strain 129Pt) OX=205914 GN=lpxC PE=3 SV=1 |
| A5UIR8 | 1.09e-205 | 1 | 305 | 1 | 305 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Haemophilus influenzae (strain PittGG) OX=374931 GN=lpxC PE=3 SV=1 |
| P45070 | 2.20e-205 | 1 | 305 | 1 | 305 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=lpxC PE=3 SV=1 |
| A5UCW3 | 4.44e-205 | 1 | 305 | 1 | 305 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Haemophilus influenzae (strain PittEE) OX=374930 GN=lpxC PE=3 SV=1 |
| Q4QLF2 | 4.44e-205 | 1 | 305 | 1 | 305 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Haemophilus influenzae (strain 86-028NP) OX=281310 GN=lpxC PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000072 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |