CAZyme Information: MGYG000000246_01587

Basic Information

• Species: Streptococcus pasteurianus
• Lineage: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pasteurianus
• CAZyme ID: MGYG000000246_01587
• CAZy Family: CE7
• CAZyme Description: Cephalosporin-C deacetylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
295	MGYG000000246_4|CGC3	33523.2	6.4233

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000246	2159802	Isolate	China	Asia

• Gene Location: Start: 81094; End: 81981 Strand: +

Full Sequence      

MIFGIKAQKEVDSLGLHYELTPTDFTSKVADCYDLYFTGVHESKIYAQLLLPKKSSAKHP
VIFQFHGYHSDVGDWLDKLAFVSEGYVVVALSVRGQGGESEDCLQTSGGTLKGHLIRGIE
DGPEKLFYRAVFQDVYQLTNVVSRLPFVDSSKMASYGVSQGGALALVCAALCPKVKRTFV
QYPFLSDYRTAYGLEVTQSAYEELAYYFRYRDPLHEREEAVFAALDYVDIQYLVDRIQAE
VIWAMGLEDRVCHPKTQFAVYNHIQAPKKLYFYPEYGHEYLPKFNDKIHQILGGK

Enzyme Prediction     

No EC number prediction in MGYG000000246_01587.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CE7	7	288	4.5e-98	0.8881789137380192

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam05448	AXE1	5.27e-101	9	292	32	314	Acetyl xylan esterase (AXE1). This family consists of several bacterial acetyl xylan esterase proteins. Acetyl xylan esterases are enzymes that hydrolyze the ester linkages of the acetyl groups in position 2 and/or 3 of the xylose moieties of natural acetylated xylan from hardwood. These enzymes are one of the accessory enzymes which are part of the xylanolytic system, together with xylanases, beta-xylosidases, alpha-arabinofuranosidases and methylglucuronidases; these are all required for the complete hydrolysis of xylan.
COG3458	Axe1	3.24e-92	6	286	30	307	Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, transport and catabolism].
COG1506	DAP2	2.34e-17	36	283	369	599	Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism].
pfam02129	Peptidase_S15	1.20e-07	44	268	4	250	X-Pro dipeptidyl-peptidase (S15 family).
COG0412	DLH	5.35e-07	54	185	22	146	Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QIX73607.1	1.41e-212	3	295	26	318
BAK29294.1	1.41e-212	3	295	26	318
SQI07740.1	1.41e-212	3	295	26	318
QCE36026.1	1.41e-212	3	295	26	318
CBI12663.1	4.04e-212	3	295	26	318

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7CUZ_A	7.08e-100	11	290	31	310	ChainA, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147],7CUZ_B Chain B, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147],7CUZ_C Chain C, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147],7CUZ_D Chain D, Acetylxylan esterase [Lactococcus lactis subsp. lactis KF147]
3FCY_A	6.22e-91	6	292	56	341	CrystalStructure of Acetyl Xylan Esterase 1 from Thermoanaerobacterium sp. JW/SL YS485 [Thermoanaerobacterium saccharolyticum JW/SL-YS485],3FCY_B Crystal Structure of Acetyl Xylan Esterase 1 from Thermoanaerobacterium sp. JW/SL YS485 [Thermoanaerobacterium saccharolyticum JW/SL-YS485],3FCY_C Crystal Structure of Acetyl Xylan Esterase 1 from Thermoanaerobacterium sp. JW/SL YS485 [Thermoanaerobacterium saccharolyticum JW/SL-YS485]
6AGQ_A	8.68e-45	24	292	49	317	Acetylxylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_B Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_C Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_D Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_E Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4],6AGQ_F Acetyl xylan esterase from Paenibacillus sp. R4 [Paenibacillus sp. R4]
2XLB_A	9.87e-43	3	284	27	304	Acetylxylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_B Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_C Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_D Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_E Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_F Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_G Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_H Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_I Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_J Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_K Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus],2XLB_L Acetyl xylan esterase from Bacillus pumilus without ligands [Bacillus pumilus]
2XLC_A	7.56e-42	3	284	27	304	Acetylxylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_B Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_C Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_D Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_E Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus],2XLC_F Acetyl xylan esterase from Bacillus pumilus CECT5072 bound to paraoxon [Bacillus pumilus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P94388	2.45e-38	9	284	33	304	Cephalosporin-C deacetylase OS=Bacillus subtilis (strain 168) OX=224308 GN=cah PE=1 SV=1
Q9WXT2	1.29e-34	28	279	52	304	Cephalosporin-C deacetylase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=axeA PE=1 SV=1
D5EXI2	3.22e-14	25	269	172	411	Acetyl esterase Axe7A OS=Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23) OX=264731 GN=axe7A PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000026	0.000041	0.000001	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000246_01587.