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CAZyme Information: MGYG000000211_02631
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides sp900556215 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides sp900556215 | |||||||||||
| CAZyme ID | MGYG000000211_02631 | |||||||||||
| CAZy Family | CBM50 | |||||||||||
| CAZyme Description | Integration host factor subunit alpha | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 407687; End: 408988 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00216 | Bac_DNA_binding | 9.34e-19 | 10 | 93 | 5 | 88 | Bacterial DNA-binding protein. |
| cd13835 | IHF_A | 4.49e-16 | 10 | 93 | 5 | 88 | Alpha subunit of integration host factor (IHFA). This subfamily consists of the alpha subunit of integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms. |
| cd13832 | IHF | 5.28e-16 | 10 | 91 | 4 | 85 | Integration host factor (IHF) and similar proteins. This subfamily includes integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms. This subfamily also includes the protein Hbb from tick-borne spirochete Borrelia burgdorferi, responsible for causing Lyme disease in humans. Hbb, a homodimer, shows DNA sequence preferences that are related, yet distinct from those of IHF. |
| COG0776 | HimA | 6.56e-16 | 4 | 96 | 1 | 93 | Bacterial nucleoid DNA-binding protein [Replication, recombination and repair]. |
| cd13831 | HU | 1.40e-14 | 10 | 91 | 5 | 86 | histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUT91726.1 | 3.89e-165 | 1 | 433 | 1 | 471 |
| QPH57227.1 | 6.81e-124 | 1 | 433 | 1 | 392 |
| QBJ16968.1 | 6.81e-124 | 1 | 433 | 1 | 392 |
| QMI81676.1 | 6.81e-124 | 1 | 433 | 1 | 392 |
| QQA31617.1 | 1.10e-122 | 1 | 433 | 1 | 392 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5J0N_I | 8.88e-09 | 12 | 93 | 9 | 90 | ChainI, Integration host factor subunit alpha [Escherichia coli],5J0N_K Chain K, Integration host factor subunit alpha [Escherichia coli] |
| 1IHF_A | 9.56e-09 | 12 | 93 | 10 | 91 | INTEGRATIONHOST FACTOR/DNA COMPLEX [Escherichia coli],1OUZ_A Chain A, Integration Host Factor Alpha-subunit [Escherichia coli],1OWF_A Chain A, Integration Host Factor Alpha-subunit [Escherichia coli],1OWG_A Crystal structure of WT IHF complexed with an altered H' site (T44A) [Escherichia coli],2HT0_A IHF bound to doubly nicked DNA [Escherichia coli],5WFE_K Cas1-Cas2-IHF-DNA holo-complex [Escherichia coli S88] |
| 2IIE_A | 7.08e-08 | 12 | 93 | 54 | 135 | singlechain Integration Host Factor protein (scIHF2) in complex with DNA [Escherichia coli] |
| 1HUE_A | 1.27e-07 | 5 | 93 | 1 | 89 | ChainA, HU PROTEIN [Geobacillus stearothermophilus],1HUE_B Chain B, HU PROTEIN [Geobacillus stearothermophilus],1HUU_A Dna-Binding Protein Hu From Bacillus Stearothermophilus [Geobacillus stearothermophilus],1HUU_B Dna-Binding Protein Hu From Bacillus Stearothermophilus [Geobacillus stearothermophilus],1HUU_C Dna-Binding Protein Hu From Bacillus Stearothermophilus [Geobacillus stearothermophilus] |
| 2IIF_A | 2.35e-07 | 12 | 93 | 54 | 135 | ChainA, Integration host factor [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q15SX9 | 4.75e-10 | 10 | 93 | 8 | 91 | Integration host factor subunit alpha OS=Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) OX=342610 GN=ihfA PE=3 SV=1 |
| B2FN73 | 6.65e-10 | 10 | 93 | 8 | 91 | Integration host factor subunit alpha OS=Stenotrophomonas maltophilia (strain K279a) OX=522373 GN=ihfA PE=3 SV=1 |
| B4SQG8 | 6.65e-10 | 10 | 93 | 8 | 91 | Integration host factor subunit alpha OS=Stenotrophomonas maltophilia (strain R551-3) OX=391008 GN=ihfA PE=3 SV=1 |
| Q65TL4 | 1.65e-09 | 10 | 95 | 8 | 93 | Integration host factor subunit alpha OS=Mannheimia succiniciproducens (strain MBEL55E) OX=221988 GN=ihfA PE=3 SV=1 |
| Q2P101 | 1.70e-09 | 10 | 93 | 8 | 91 | Integration host factor subunit alpha OS=Xanthomonas oryzae pv. oryzae (strain MAFF 311018) OX=342109 GN=ihfA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000070 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
