CAZyme Information: MGYG000000196_01953

Basic Information

• Species: Bacteroides thetaiotaomicron
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides thetaiotaomicron
• CAZyme ID: MGYG000000196_01953
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
783	MGYG000000196_7|CGC5	88903.38	6.8162

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000196	6397474	Isolate	China	Asia

• Gene Location: Start: 260912; End: 263263 Strand: -

Full Sequence      

MKNRILFSVFALVAVTLFAQGKQKDFVLQSGQPVVIACSGSEAPVVHTSLDLLSRDLQTV
LSATAHVDTNTGNIIVGTIGQSKLIEQAGIDISALKNKKQAFLLTVSEDGKLVVAGSDSH
GTAYGILEISRLLGVSPWEWWADVTPEKKETFRLSGKFRELQSPSVEYRGIFINDEDWGL
MPWSNKTYEPSDVKGEIGPRTNERIFELLLRLRANTYWPAMHECTLPFFLTKGNREAAKK
YGIFMGASHCEPMACSAAGEWRIRGKGAYDYVNNSPAVYQFWEDRVKEVAGQEILYTLGM
RGVHDGKMQGAKTVEEQKAVLDRVFVDQRGLLEKYVNKDVTQVPQVFIPYKEVLDIYHAG
LQVPEDVTLMWCDDNYGYIRHFPTAEERARKGGNGVYYHVSYWGRPHDHLWLSTMSPSLI
YQQMKQAYDQGIQKMWILNVGDIKPAEYQIELFMDMAWNLDKVSSEGVTAHLKHWLEREL
GTSCAKAILPVMQEHYRLAHIRKPEFMGNTREEEKNPVYREVKDLPWSEREINERLNAYS
QLSEMVEKAASKVPADRQSAYFELVKYPVQAATQMNRKLLYAQLARHDKEDWEKSDAAYD
SIAALTQHYNSLENGKWNRMMDFKPRKLPVFNRVERNAATAPMTADRKAACQWNGAEAKK
GNAIVCEGLGYEGKAAEIRKGDALTFSFGNLKTDSVEVDIRLLPNHPVQDDKLRFSVSLD
GAEPEVIAYETKGRSEEWKENVLRNQAIRKIVLPVLGRKSHQLVIKALDEGVILDQVMLY
EVN

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	26	777	2.3e-250	0.994261119081779

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	162	506	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	2.99e-13	680	780	54	159	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QQA08841.1	0.0	1	783	1	783
ALJ39737.1	0.0	1	783	1	783
QUT73086.1	0.0	1	783	1	783
QUT40935.1	0.0	1	783	1	783
AAO78064.1	0.0	1	783	1	783

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5BY3_A	0.0	23	783	17	777	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4ZMH_A	1.13e-100	68	618	62	607	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
4C90_A	4.59e-95	1	621	12	640	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PXQ_A	3.43e-89	28	624	19	627	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PUG_A	3.50e-89	28	624	20	628	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000510	0.998511	0.000453	0.000162	0.000163	0.000165

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000196_01953.