CAZyme Information: MGYG000000150_03075

Basic Information

• Species: Hungatella sp005845265
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella; Hungatella sp005845265
• CAZyme ID: MGYG000000150_03075
• CAZy Family: GH2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
819	MGYG000000150_12|CGC3	94511.76	4.9462

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000150	7470188	Isolate	United Kingdom	Europe

• Gene Location: Start: 174800; End: 177259 Strand: -

Full Sequence      

MVIQKVTEGWKVRSCQTGQCFETKVPGTVYGTWLEHGAMEDPYWRDCEDDALAMMEGEYE
YETTLPFCEELMSCRAIRLKFEGIDTLADIYFNGNHLGVADNMHRVWEYPVKSLAAESGG
VNTIRVRFHSPLSFIKEAYEKSPYDGSPEAMQGFPLLRKSHCSFGWDWGPRLPDAGLFRP
VSLVGVEQAEIRDVWIRQIHREGTVSLSCDIAVESVCDTVCTCELKVTGPKGDTSVSQLQ
RKNDGFFGGIVIDNPELWWPNGYGSQPLYRVEAVLKANGEIQDIQSRMVGLRTMKVNTGA
DEYGSRFAHEVNGVEIFAMGADYIPEDCIRGRVNRERTRTLLEHCRDCNFNVIRVWGGGY
YPDDFFYDLCDELGLIVWQDFMFACAVYPLTPEFEANVTAEIRDNVRRIRHHACLGLWCG
NNEMEMFLANNQWVRKPLQKTEYLIMNERIIPELLRQYDPDTFYWPSSPSSGGDFDSPND
PDRGDVHYWEVWHGGLPFTDYRNYYFRYLSEFGFQSFPAVKTIEQFTAPEDRNIFSYVME
KHQKNAGANGKILQYMSQMYLYPESLELLVYVSQLLQAEAIRYGVEHFRRNRGRCMGCVY
WQLNDCWPVASWSSIDYYGRWKALHYFAKRFFAPVLLSCEEEGALSSSMNVNEENRRIRK
AARFCVTNETRERITGVIRWSLRDASSRIHQQGQYCVEAEPLSVCSFPQMEFTEADMRRW
YLSYELWIGDRRVSHGSSLFVPPKHFEFEDPQLEVWQEGEMVCIRSSAFAKGVELGNKDG
DLLLSDNYFDMDAGVERVRVMQGSMEGLSVRSIYSLAHA

Enzyme Prediction     

No EC number prediction in MGYG000000150_03075.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	5	667	1.1e-97	0.636968085106383

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	3.41e-99	1	644	10	641	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340	ebgA	2.31e-13	79	423	130	449	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam00703	Glyco_hydro_2	1.41e-12	191	292	3	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam17786	Mannosidase_ig	2.02e-07	666	745	7	91	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
PRK10150	PRK10150	8.25e-07	175	423	168	417	beta-D-glucuronidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADL35923.1	0.0	1	813	1	820
QBE97789.1	0.0	1	816	15	836
QQQ93614.1	0.0	1	816	1	822
ASU28856.1	0.0	1	816	1	822
ANU76049.1	0.0	1	816	1	822

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2VJX_A	1.36e-150	9	638	14	657	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	1.44e-150	9	638	16	659	Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A	1.48e-150	9	638	16	659	ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A	3.89e-150	9	638	14	657	Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]
2VQU_A	1.61e-148	9	638	14	657	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQU_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q0CCA0	2.08e-101	4	642	7	661	Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2
Q95327	4.48e-100	10	636	29	692	Beta-mannosidase OS=Capra hircus OX=9925 GN=MANBA PE=1 SV=1
O00462	2.34e-99	25	636	44	692	Beta-mannosidase OS=Homo sapiens OX=9606 GN=MANBA PE=1 SV=3
Q29444	2.34e-99	10	636	29	692	Beta-mannosidase OS=Bos taurus OX=9913 GN=MANBA PE=1 SV=1
Q4WAH4	4.41e-98	25	642	32	663	Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000044	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000150_03075.