CAZyme Information: MGYG000000150_01565

Basic Information

• Species: Hungatella sp005845265
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella; Hungatella sp005845265
• CAZyme ID: MGYG000000150_01565
• CAZy Family: GH59
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
2412	MGYG000000150_5|CGC4	265508.69	4.2612

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000150	7470188	Isolate	United Kingdom	Europe

• Gene Location: Start: 254833; End: 262071 Strand: -

Full Sequence      

MKMKQMAKQSLCFLLSAGMVMNSGMMFNPPAYAAADSNVHEITVDGDVIDPVNTFRGFGA
VTCNNTSRLLMDYKEEHPDKYWEMMELLFNPEKGAGLNHIKVEMGGDVNSSSGTEPATMR
SPEEEANVLRGAGWHFAADAKTINPDITVEILRWGEPKWTQEGIGYETSENPKYEARYQW
YKKTIDAVYDEYGYEINYVSPGQNERRRDYGDNTAWIKYCANRLNEDAEKEDARYDYSQI
QIVAADTHSNSKDIAGRMLSDSELMDLVDVVSDHYTLYGNSDLTKVNQEYGKEIWYSEAI
APMINAKYRINVDPDRGGVGGKVGMADLATRFINSYSYSDAGDNPARMTRFEFQPAIGAF
YEGSAYSPKQLIGAFDPWSGYYDADGGLQMVGHFMEFADLGWNYLPDACYGDGSYSDGGV
LADTGTNNYLTLKDPDTDDYSMIFANNTSQTRKYKVTVKNLKKASSPLNVWETRGPDEGQ
EYDSNWMQMVDSFTPNKESYGVYSFTLTVKPYSIKTVTSLLDRGQEYSPGQNDPNVDRDV
LALPYTDDFEYADYDTDEKGRTYLERRGGTPRYTTDQYGAFEVREGSFGNHVLTQMINYD
NRPYDWNVWGNGTDENSQTTGRPRTVLGDHRWTNYTAGIDFKLDLTSPECFENYAGIGVR
EVVHEGTNANDIATYTFQVFQNGSYQLSCRTGKSVKGTLENFDSTVWHNMQLSADENVLT
AYVDGKKAAELVDDNHTSMSGRVTLTSGFYNTQFDNLEVLPIEGKAAAAEQKLDDTSELI
TWNGNWNHVLNEGYGHYNRTRTYGGSIEKGVYAHNSGQIRYYKGGNPLAWGSNDSNAWGS
AADEAHYEFDFYGTGIEIFGEANGSNGTGDVYVDGEKVGTVNYNSGNGGTGHNVFNLDLD
PDQLHTLKVTATSSFISLQKLKVIGEPDDSGESRENSFSLTFHGTGIQVFGNSGAATIKV
EVDGEIREAAYQTPAAGNRQTTYALQNLPEGEHTVKITVEGGTYYVDGIDVLGTAAEGAA
VNTAKLLTLIDTAKKLTNDDETYMPEDWENFRKAITAAEEALAGGSAEAVNQAYLALRNA
MEKLGLAGAITEVTGLEKLYITTKGTVPRMPDRVSIIRLDGKVSEADVVWNLSEEQFDTV
YKTVEVTGEAGEDKYPVKARVMTVPQELRYYIDCAADVPVNPNGGGALEIRSSVYEAVEK
YFEAGGKALLNDTADQKYGSAAEQWGFEITDSKNPLKPSPDGAEGEYDNSYTAGWRTNGS
EIVYHLTLDAGTYKITNGFHDWYGSRSRDMRPELIYKDENGQEQKITFDTILSRGTDMAV
TNKFTLPVSGDVTYKLVHAANEKPIISWLAVEESANLTSIEVSKMPDKTMYSIGEKLDTT
GMEVTGYYDNGTERKLSDSQYSVSGFDSSVPGEKTVTITAKEDNVTATVKVTVGGDSVED
IPVLPVVAAEDQLPETLTLKVNGEIRDTAVTWNLKEGDWSLPGSTVKLEGVLENLDAGTI
SWSPVVYSSTQVYFIDCGIGVKRGTVDNTGRTSEIFNAVHDAVKYLKNDVPDQAGDGNSW
GSGSDYDGIKGYEENHGLHATGYFGKNSIGDSFTYKVTLDAGEYNITTGHTEWWSGNSRT
TKVTASYIGTDGTVVKTELGSSGSTGGTQWKELYVQGHLSVPENDTEVTLTFTAAEAKGA
AVSYIAIERGEAPVTKQAINKIKVDTMPNKTVYELGEEFEPVGMVINGYHGSELVRELKE
EEYTMDGPDMNEAGLSKVTITYEDENGKEYSAIFRVTVYDPEDLRADSIKVVREPEKTVY
LPGENFDADGMEVRLLLKATASNAVPARAEKLEDGEYDVVSDLSDPGRRSVEICYSYFDD
NGEEKVLRDTIKVTVLDEEDEFYQKGISIAKQPKKTVYPVDGQFDPEGMEVETVMKASTS
NASYAEKTLDYEIGKYDFSEPGNKKIKVTQTGTGKDGEEKDFTAVIEVTVTENEALVMED
RLDSVIRDASEIFDNDTAAYRTIKEKQDAASALRHSAAESFAEYEGELSKTMVRQIGELE
DYFMEAYPNITVRVSGDRNLTEGAAVTGAVLSADAEQENQVITLMMEEAEIPDGLPEVKA
VKAMDIRLMVSDEEIQPVVPLFLTARIPEGISQKNLVIYHVTESGEIETIIPETADNMMS
FGVSSLSTFAVANPGTLTVTGIRITAKPYKTVYQIGESFEADGMVVTAVYENGTEAVVTE
YELSSFDSASAGIKHVVITYGGRKAILDVTVKSETGDEPDDGDNPGSSGGSGSSGSSSGS
RPRVNTTSTVTGTWMQDQTGWWFAKTAGGYVKAEWAQINGTWYYFGEDGYMRTGWILSGN
QWYYLQPDGSMTDNNWICYKDHWYFLQPGGAMAVSGWVTWNGRSYYLNADGTMAVNTTTP
DGYVTGADGARI

Enzyme Prediction     

No EC number prediction in MGYG000000150_01565.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH59	53	759	3.4e-177	0.9857369255150554

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam02057	Glyco_hydro_59	3.21e-106	55	394	1	291	Glycosyl hydrolase family 59.
COG5263	COG5263	1.73e-25	2286	2412	188	313	Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism].
NF033838	PspC_subgroup_1	1.08e-23	2285	2409	499	622	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
NF033930	pneumo_PspA	1.46e-23	2291	2394	483	582	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
NF033838	PspC_subgroup_1	3.75e-23	2291	2410	486	603	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AYA75976.1	2.04e-261	35	1094	35	1264
QNM42518.1	1.72e-252	42	1023	41	1114
QLD11141.1	1.47e-251	41	1614	62	1439
QJW36728.1	4.08e-251	41	1351	67	1193
AEI43030.1	5.46e-249	4	1084	5	1262

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4CCC_A	2.81e-34	55	759	25	650	StructureOf Mouse Galactocerebrosidase With 4nbdg: Enzyme-substrate Complex [Mus musculus],4CCD_A Structure Of Mouse Galactocerebrosidase With D-galactal: Enzyme-intermediate Complex [Mus musculus],4CCE_A Structure Of Mouse Galactocerebrosidase With Galactose: Enzyme-product Complex [Mus musculus],4UFH_A Mouse Galactocerebrosidase complexed with iso-galacto-fagomine IGF [Mus musculus],4UFI_A Mouse Galactocerebrosidase complexed with aza-galacto-fagomine AGF [Mus musculus],4UFJ_A Mouse Galactocerebrosidase complexed with iso-galacto-fagomine lactam IGL [Mus musculus],4UFK_A Mouse Galactocerebrosidase complexed with dideoxy-imino-lyxitol DIL [Mus musculus],4UFL_A Mouse Galactocerebrosidase complexed with deoxy-galacto-noeurostegine DGN [Mus musculus],4UFM_A Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ [Mus musculus],5NXB_A Mouse galactocerebrosidase in complex with saposin A [Mus musculus],5NXB_B Mouse galactocerebrosidase in complex with saposin A [Mus musculus],6Y6S_A Chain A, Galactocerebrosidase [Mus musculus],6Y6T_A Chain A, Galactocerebrosidase [Mus musculus]
3ZR5_A	2.86e-34	55	759	27	652	STRUCTUREOF GALACTOCEREBROSIDASE FROM MOUSE [Mus musculus],3ZR6_A STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE IN COMPLEX WITH GALACTOSE [Mus musculus]
4FDW_A	3.67e-09	1355	1422	21	91	Crystalstructure of a putative cell surface protein (BACOVA_01565) from Bacteroides ovatus ATCC 8483 at 2.05 A resolution [Bacteroides ovatus ATCC 8483]
4FD0_A	4.61e-08	1355	1422	24	94	Crystalstructure of a putative cell surface protein (BACCAC_03700) from Bacteroides caccae ATCC 43185 at 2.07 A resolution [Bacteroides caccae ATCC 43185]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q0VA39	1.47e-35	33	759	31	672	Galactocerebrosidase OS=Xenopus tropicalis OX=8364 GN=galc PE=2 SV=1
Q498K0	1.43e-34	33	759	31	671	Galactocerebrosidase OS=Xenopus laevis OX=8355 GN=galc PE=2 SV=2
P54803	1.12e-33	55	759	55	681	Galactocerebrosidase OS=Homo sapiens OX=9606 GN=GALC PE=1 SV=3
P54804	1.75e-33	55	759	39	665	Galactocerebrosidase OS=Canis lupus familiaris OX=9615 GN=GALC PE=1 SV=1
P54818	1.97e-33	55	759	55	680	Galactocerebrosidase OS=Mus musculus OX=10090 GN=Galc PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000432	0.998780	0.000181	0.000229	0.000187	0.000168

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000150_01565.