CAZyme Information: MGYG000000069_02097

Basic Information

• Species: Clostridium_A leptum
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Clostridium_A; Clostridium_A leptum
• CAZyme ID: MGYG000000069_02097
• CAZy Family: GH95
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1571	MGYG000000069_6|CGC3	172791.28	4.0203

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000069	3099132	Isolate	United Kingdom	Europe

• Gene Location: Start: 58243; End: 62958 Strand: +

Full Sequence      

MKKGKRKSILAKLLSCVMVLQVAASFGASSYAAESESGTSVTPIFNPDYAQLIGRSDISY
TGQISNGMQGFSVANGRFGGPVWQSTDSTLTMQVNHTSVFMFNDASSVSKDHLNSGGGGI
GRIHVNFGGSVFGGDTENYLSLYEGRLDVTTPEVAVEVLPNMDLDSDAIILRVTDNREVP
EDITIDLTMLRDANQVWGDEGQHTVTSVLSKEADGSTAVLEQLIQEDCDTGIESNDHYNH
AAMAVTVQERSVSSIEESKVGNRDSMQLTVPAATGSFTIVVGGDASMSEDDDVVANAIAS
AAQSPSYDEVSASSAAWWADFWNQSYIYLPSQQNFEQRRNYYMYLAAISNRGSYPSKYNG
GIWLAEEDRRDWGSFYWNWNQDSLYQPLMAANHVDLMDPLFEMRESSYDQYAVAAEQMWG
SEGIYIPETCGVLGWETLPDDIAESVREYYTFETDQRSQDFTDMTKRRNTYLAAWNWNVF
GNSDNQASYTTHTMMATQETAEYYWQRYCYTKDLDWLRDHAYDFIKGAAELYRTYPGFVK
EDDGKYHIYNTNLHEHIWAGKDVIDDLSMARGVFAAAVEASELLGVDEELRALWIDCRDN
MASYPLRTDEGAVWAGSTNESMKESLATDEPAWAQGLAPYYFIRDCHGTESPIFKMLEKY
DILNLETRDQGLDNGDWEIALNTYYHSPGYLNQFEGTKVDQNGSSRFHVDVAKLGLGDDL
GRILNTQYEVFTVNGDTPNLIFDQRDYYSAEGYGTFSAALQDGLNQSLAPTTDGDPVIRV
FPAWPKAWDAKYKLLAKDGFLVSSSIESEEIQYVEIESQLGETCRVRNPWDCSVVLYRNG
VKAETIEAGENDLMEFETSENEVIVLVKEGTTPDQYRTSELTSVDYHTVNDTESNIIYTG
DWTYSENRTDREDYLNDVHYTTADGDSVEYTFTGNGVEFITETGPEMGEIDVYIDGELKT
TIDCSSPENILYQQTVYRNAGLKFEYPVGGSEYQGRHTIKLVKKSGQAMIVDAFKILTEE
DAAEYDADNMNEKIININDNDLDYIEYVDASGATDRNDGAWFYTDNRAGEGAYMNDAHIC
GNSSSGGIGNYCEVTFTGTGITYLTERNNDMGEVKVYLDGEEQETVSCYKTGGRDSRYPV
YSVSGLENKEHTLRLEKVSGQYMIVDYFEVTVPTGLGDVTGIELVQQPSLVYDEGQPLDL
SALKILVTYENGAEKLLSYDDADIQVSVAGGAPVAHGDELTADYNGKALAISYGSQSVET
DPLQVGFESVFADDTHSSVKYIGSTWSAETNREDAYNGTVHIAGSAKELGNGDYCEFSFN
GIGASFLTERNENMGKIDVYVDGILRATVDCSAAEGDSQYAAYTVLGLPEGKHTLKLVKA
SGDYMIVDAFEVWGTLIEEVTLESISVTGPTKAEYEIGDELDLDGLVVTAHYSDDSSKPI
TEGYEVAGFDSSTAGEKTVTVSYEGKTATFKVTVKEASSEQPGGDSSVPSGSEPSGSSEP
SGSSEPSGSSEPSGSSEPSGSSEPSEPAGSSESETPETGDHSMTLVLPVVSVLALAILGA
AILVLYQKKRV

Enzyme Prediction     

No EC number prediction in MGYG000000069_02097.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH95	166	616	1.1e-24	0.554016620498615

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07523	Big_3	5.55e-14	1409	1474	1	67	Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.
pfam17996	CE2_N	3.10e-04	1089	1163	19	88	Carbohydrate esterase 2 N-terminal. This is the N-terminal beta-sheet domain with jelly roll topology found in CE2 acetyl-esterase from the bacterium Clostridium thermocellum. This enzyme displays dual activities, it catalyses the deacetylation of plant polysaccharides and also potentiates the activity of its appended cellulase catalytic module through its noncatalytic cellulose binding function. This N-terminal jelly-roll domain appears to extend the substrate/cellulose binding cleft of the catalytic domain in C.thermocellum.
pfam17996	CE2_N	5.83e-04	925	1005	19	84	Carbohydrate esterase 2 N-terminal. This is the N-terminal beta-sheet domain with jelly roll topology found in CE2 acetyl-esterase from the bacterium Clostridium thermocellum. This enzyme displays dual activities, it catalyses the deacetylation of plant polysaccharides and also potentiates the activity of its appended cellulase catalytic module through its noncatalytic cellulose binding function. This N-terminal jelly-roll domain appears to extend the substrate/cellulose binding cleft of the catalytic domain in C.thermocellum.
pfam17996	CE2_N	0.002	1312	1381	19	84	Carbohydrate esterase 2 N-terminal. This is the N-terminal beta-sheet domain with jelly roll topology found in CE2 acetyl-esterase from the bacterium Clostridium thermocellum. This enzyme displays dual activities, it catalyses the deacetylation of plant polysaccharides and also potentiates the activity of its appended cellulase catalytic module through its noncatalytic cellulose binding function. This N-terminal jelly-roll domain appears to extend the substrate/cellulose binding cleft of the catalytic domain in C.thermocellum.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QJD84034.1	0.0	3	881	2	880
QGQ97246.1	1.77e-52	889	1392	907	1375
BBI32659.1	3.24e-46	888	1392	132	493
QLG41554.1	1.32e-44	688	1388	297	1046
AYQ75813.1	7.78e-41	886	1392	1035	1569

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A0A401ETL2	9.91e-13	1401	1497	1372	1473	Exo-beta-1,6-galactobiohydrolase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=bl1,6Gal PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000252	0.998931	0.000255	0.000194	0.000180	0.000157

TMHMM  Annotations     

start	end
1544	1566