CAZyme Information: MGYG000000038_00821

Basic Information

• Species: Dorea_A longicatena
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Dorea_A; Dorea_A longicatena
• CAZyme ID: MGYG000000038_00821
• CAZy Family: GH146
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1348	MGYG000000038_2|CGC3	149071.1	4.4963

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000038	3124256	Isolate	United Kingdom	Europe

• Gene Location: Start: 353274; End: 357320 Strand: -

Full Sequence      

MKGEELISWNKNEWYTDGWYLSSENDNTPLTLSVGPAKTNGQPYRVSVSGKRSEFLPTGE
WTHIAVTYDKDSKEICFYRNGVKCSTVTTYGIGGESTGVLGSDASMEKSIGYNGPKYKGA
YLKASLDEYQLYNDVATQEEVIALYEESGQTFDRKAVAQADLDKISIPETTQGNLSLPAT
GESGSVISWSSDNEAVVAADGTVVRPGVGEKDATVTLTAEASYLNGEKVTKTYKVTVTAK
QEINITTNSIMGDVTLEDDYLVNAAQKEDEYLLSLDSEKFLYEFYKISGLTPKTDSEYEG
WERSHGNNFRGHTFGHYMSALSQAYLSADGDTKAALKTEIKEAVDGLKECQDAYAAKYPD
SAGYVSPFPEEWLKDKDGVNLANTKKVSGDTVYVPYYNLHKVLAGLIDVTKNVDDQEIKE
TALSVAEGFGEYLNNRLSKLTDKSKMLRTEYGGMNEALYELYNITGNDHYKTAAQYFDET
DLFTKLANNQDVLNGLHANTTIPKLTGALKRYTVLTEKEDYYNSLSDSEKSSLEMYLKAA
ENFWQITVDHHTYVTGGNSQSEHFHEADKIGYDATKSEYDASTTCETCNTYNMLKLSKAL
YQVTGDKKYMDYFETTYTNAILSSQNPETGTTMYFQPMAPGYNKVFNRPFDEFWCCTGTG
MENFSKLGDNIYTVSEDSVAVQMFYSSELKDDTHNLKLKQIANMPNEDKITLQVSAADGG
QVAEGTDLKLRKPDWIAGDAAITVNGKTVKAEEQNGYFVIADVKAGDEITYQMPMKVTAY
TMPDKSNMVAFKYGPVVLSTALSTNNIEASNPNGILVRVGTYDSSCQTVITVESDSVETW
LKNLEKNMVRIEDSADGQVQFKLKNVDSESENLIYTPHYMRYKERYGLYMYMEEADSKSS
QDRILENKKSIRDTEMSTDSLYTFDDNNSEAAKNQQGENTSVGVFNGKGYRHGEKNTGWF
SYDLKIDPTAEKNYLNCTYYSGDNGRTFDVYVNGQKLKTVTINTAAGTNTFYVDTTEIPA
EYLTEGSDTITVKFQAIPGKNSYVGGLFGISTSSSTAYDTDASLAALSFDKGTMTPAYDK
DTTEYVLEVPEDTETVAMTATPKKESGLVYVGDVLIDDKHPRNIALTEEETVVNLTSKAQ
DHETEQAYKITIKKVKKTEQELAIVTDPSDYKGIVGETAEFTVEATGEGLTYQWEYCNAG
SSKWRTSSMAGSDTATIKVSVGTWRDGQKYRCVVKDAAGNTVTSKEAVMTVGKADTAPVI
TAQPESVTKNKGETAEFTVEATGEGLTYQWEYCNAGSDKWRTSSMEGNQTATIKVAAGSW
RNGQKYRCVVTGTDGRIVVSEAAVLTVK

Enzyme Prediction     

No EC number prediction in MGYG000000038_00821.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH146	253	799	3.1e-171	0.9980119284294234

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	1.70e-131	253	799	1	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	1.36e-87	254	812	12	507	Uncharacterized conserved protein, DUF1680 family [Function unknown].
pfam13385	Laminin_G_3	6.94e-10	17	141	43	150	Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.
pfam12733	Cadherin-like	5.56e-05	1073	1148	5	82	Cadherin-like beta sandwich domain. This domain is found in several bacterial, metazoan and chlorophyte algal proteins. A profile-profile comparison recovered the cadherin domain and a comparison of the predicted structure of this domain with the crystal structure of the cadherin showed a congruent seven stranded secondary structure. The domain is widespread in bacteria and seen in the firmicutes, actinobacteria, certain proteobacteria, bacteroides and chlamydiae with an expansion in Clostridium. In contrast, it is limited in its distribution in eukaryotes suggesting that it was derived through lateral transfer from bacteria. In prokaryotes, this domain is widely fused to other domains such as FNIII (Fibronectin Type III), TIG, SLH (S-layer homology), discoidin, cell-wall-binding repeat domain and alpha-amylase-like glycohydrolases. These associations are suggestive of a carbohydrate-binding function for this cadherin-like domain. In animal proteins it is associated with an ATP-grasp domain.
pfam07679	I-set	6.25e-04	1258	1347	1	90	Immunoglobulin I-set domain.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEI10685.1	0.0	3	1152	121	1289
QDP74899.1	0.0	1	1152	125	1290
ARK06383.1	0.0	1	1152	125	1290
QUB98427.1	0.0	1	1152	125	1290
QJW37681.1	0.0	1	1152	125	1290

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6YQH_AAA	1.81e-92	251	997	30	750	ChainAAA, Acetyl-CoA carboxylase, biotin carboxylase [Bacteroides thetaiotaomicron VPI-5482]
5OPJ_A	3.93e-88	251	997	30	750	Beta-L-arabinofuranosidase[Bacteroides thetaiotaomicron]
5MQO_A	5.66e-09	534	856	317	673	Glycosidehydrolase BT_1003 [Bacteroides thetaiotaomicron]
5VF3_Z	8.21e-07	1094	1317	18	259	ChainZ, Highly immunogenic outer capsid protein [Tequatrovirus T4]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P18056	4.50e-06	1094	1317	18	259	Highly immunogenic outer capsid protein OS=Enterobacteria phage T4 OX=10665 GN=hoc PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999991	0.000033	0.000002	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000038_00821.